PREDICTIVE SIGNIFICANCE OF NITROGEN OXIDE IN COMMUNITY-ACQUIRED PNEUMONIA ASSOCIATED WITH TORH INFECTION IN CHILDREN

Nargis Hayrullaevna Mirsalikhova Republican Specialized Scientific and Practical Medical Center of Pediatrics, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan E-mail: nargis080@yandex.ru
Furkat Mukhitdinovich Shamsiev Republican Specialized Scientific and Practical Medical Center of Pediatrics, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan E-mail: furkat_shamsiev8388@mail.ru
Nigora Davlyatovna Azizova Republican Specialized Scientific and Practical Medical Center of Pediatrics, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan E-mail: nigora755@mail.ru
Nargiza Fatxullayevna Nurmatova Republican Specialized Scientific and Practical Medical Center of Pediatrics, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan E-mail: nargiza-nurmatova78@yandex.ru

Abstract

The aim of the study was to assess the prognostic significance of nitric oxide indicators in community-acquired pneumonia associated with mycoplasma, herpesvirus and chlamydial infections in children. The results of the study showed that community-acquired pneumonia associated with mixed infection occurs in 15.9% of the total number of children with bronchopulmonary pathology and develops against the background of unfavorable perinatal and intrapartum periods. The study of the oxide system showed that in children with community-acquired pneumonia in combination with mixed infection, there is an increase in the level of end products of nitric oxide metabolism and are characterized by changes in nitric oxide and its metabolites, increased oxidative stress, leading to the formation of peroxynitrates and to the separation of oxidative phosphorylation processes and concomitant a cycle of changes in the form of inflammation.

 

 

 

Keywords:

community-acquired pneumonia, TORSH infection, nitric oxide, prognosis, children.

 

 

 


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