THE RESULTS OF THE USE OF LOW-INTENSITY PHOTODYNAMIC LASER THERAPY IN PATIENTS WITH DYSTROPHIC DISEASES OF THE VULVA

Delya Fozilovna Porsokhonova Doctor of Medical Science, Senior Researcher, Head of Research Group of Experimental Scientific Laboratory (ESL), Study of STIs and Reproductive Disorders, Republican Specialized Scientific and Practical Medical Center of Dermatovenerology and Cosmetology, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan e-mail: delya.porsokhonova@mail.ru
Sevara Nodirbekovna Rakhmatullaeva Junior Researcher of the Applied Project PZ-20170927338, Republican Specialized Scientific and Practical Medical Center of Dermatovenerology and Cosmetology Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan e-mail: sevararakhmatullaeva.sr@gmail.com
Marianna Leontevna Rosstalnaya Junior Researcher of the Applied Project PZ-20170927338, Republican Specialized Scientific and Practical Medical Center of Dermatovenerology and Cosmetology Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan
Bobir Shavkatovich Fattakhov PhD, Republican Specialized Scientific and Practical Medical Center of Dermatovenerology and Cosmetology, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan
Jahongir Raxmatovich Turdiev Republican Specialized Scientific and Practical Medical Center of Dermatovenerology and Cosmetology Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan

Abstract

According to the current classification, among the pretumor diseases of the vulva, united by the single term “Dystrophic diseases of the vulva” (DDV), there are sclerotic lichen (the clinical historical term “kraurosis of vulva”), squamous hyperplasia of the vulva (a similar treatment is “leukoplakia”) and other dermatoses. The aim of our study was to evaluate the results of complex therapy for patients with DDV using a low-intensity photodynamic laser. We examined 78 patients with dystrophic diseases of the vulva, among which there were simple lichen vulva (limited neurodermatitis), scleroatrophic lichen of vulva (SAL), leukoplakia. The diagnosis was histologically confirmed. Late treatment and low adherence to examination and treatment by women with DDD may contribute to the development of dystrophic and dysplastic processes in the vulva and lower third of the vagina.

 

 

 

Keywords:

dermatology, skin disease, gynecology, cosmetology, vulva

 

 

 


Full Text:

PDF


References



1. Ashrafyan L. A., Kharchenko N. V., Kiselev V. I. et al. Cancer of the vulva: epiopathogenetic concept. M., 2006, p. 192.
2. Kuznetsov V.V., Korzhevskaya E.V. Squamous cell carcinoma of the vulva. / Rational Pharmacotherapy in Oncology: A Guide for Practitioners under the General Ed. Academician of RAS M.I. Davydov, Professor V.A. Gorbunova - M .: Publishing house "Literra", 2015. - P. 441-444
3. Makarov O.V., Khashukoeva A.Z., Kupeeva E.S. Photodynamic therapy as a promising method for the treatment of dystrophic diseases of the vulva // Lech. doctor. 2011. No. 11. P. 28.
4. Sadykov R.A., Kasymov K.R., Sadykov R.R. Technical and scientific aspects of photodynamic therapy. - Tashkent. 2012.-167p.
5. Tsyb A.F. Clinical aspects of photodynamic therapy / A.F. Tsyb, M.A. Kaplan, Yu.S. Romanko, V.V. Popuchiev // Kaluga: Publishing house of scientific literature N.F. Bochkareva, 2009 - 203 p.
6. Sharapova L.E. On the etiology and pathogenesis of chronic dystrophic diseases of the vulva // Russian Bulletin of Obstetrics and Gynecology. - 2010. - No. 1.- S. 29-34.
7. Greer BE, Koh WJ. New NCCN Guidelines for Vulvar Cancer. J Natl Compr Canc Netw 2016; 14: 656–658.Greer BE, Koh WJ. New NCCN Guidelines for Vulvar Cancer. J Natl Compr Canc Netw 2016; 14: 656–658.
8. Micheletti L, Preti M, Radici G, Boveri S, Di Pumpo O, Privitera SS, Ghiringhello B, Benedetto C. Vulvar lichen sclerosus and neoplastic transformation: a retrospective study of 976 cases. Journal of lower genital tract disease. 2016 Apr 1;20(2):180-3.
9. Dunaevskaya V, Tzerkovsky DA. Photodynamic Therapy in Vulvar Dystrophy Treatment. Archives of Clinical and Biomedical Research. 2018;2(2):42-51.
10. Singh N, Ghatage P. Etiology, clinical features, and diagnosis of vulvar lichen sclerosus: a scoping review. Obstetrics and gynecology international. 2020 Apr 21;2020.
11. Levine EM. Lower Genital Tract Disease. InAmbulatory Gynecology 2018 (pp. 163-174). Springer, New York, NY.
12. Goodman A. Delay in diagnosis and increasing incidence of vulvar cancer: a root cause analysis. Menopause. 2021 Feb 1;28(2):111-2.
13. Schwartz M, Blank SV. Vulvar Cancer. Obstetrics and Gynecology. 2020 Aug 12:351-8.
14. Bratila E, Cirstoiu M, Mehedintu C, Berceanu C, Bohiltea R, Toader O, Comandasu DE. The effect of chronic vulvar dystrophy on urinary continence in patients at climacterium. Maturitas. 2017 Jun 1;100:169.
15. Singh N, Mishra N, Ghatage P. Treatment Options in Vulvar Lichen Sclerosus: A Scoping Review. Cureus. 2021 Feb;13(2).

Refbacks

  • There are currently no refbacks.