STATE OF COMMON CAROTID ARTERIES IN CHILDREN WITH EXOGENOUS CONSTITUTIONAL OBESITY ACCORDING TO ULTRASOUND RESEARCH

Guzaliya Khasanova Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
Shoira Agzamova Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan

Abstract

Introduction. Recently, obesity has been defined as a new chronic non-infectious "epidemic" that has significantly "rejuvenated" in recent years. A high risk of developing cerebral complications in obesity is associated with the formation of endothelial dysfunction, which prevents adequate regulation of cerebral blood flow. The available literature lacks data describing the structural and functional changes in the cerebral vessels in obesity in children without arterial hypertension. In this regard, it was of interest to study the state of the arteries in children with exogenous constitutional obesity. Materials and methods. We examined 137 children aged 13-17 years with different body weights by the method of random sampling. All subjects were divided into 3 groups depending on the body mass index (BMI). All patients underwent ultrasound examination of the common carotid arteries at the extracranial level. Results. In children with exogenous constitutional obesity, the diameters and thickness of the intima-media complex of the common carotid arteries are increased, as well as the blood flow velocity is reduced and the stiffness of the arterial wall is increased. The correlation of changes in the thickness of the intima-media complex of the common carotid artery with clinical and metabolic determinants of insulin resistance, atherogenic factors, as well as hypoadiponectinemia was revealed. Conclusion. The study showed that, in comparison with children of normal weight, children with obesity have non-physiological changes in the vascular wall, manifested by higher values of TCIM, deterioration of the elastic properties of the CCA and a decrease in the blood flow rate in it.

 

 

 

Keywords:

children, exogenous-constitutional obesity, common carotid arteries, vascular ultrasound, arterial stiffness, highly sensitive C-reactive protein, adiponectin.

 

 

 


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