This scientific study shows the study of morphological and morphometric indicators of hyaline membrane disease in premature infants. The material was obtained based on the results of clinical and anamnestic analysis and lung tissue of premature infants aged 22-37 weeks. The results show that immaturity of the lung tissue, circulatory disorders and damage to the alveolar and bronchial epithelium play an important role in the development of hyaline membrane disease in the lungs of premature infants. The results of morphometric studies showed that only 1/3 of the lungs of infants born at the age of 22-27 weeks had air in the alveoli, the thickness of the alveolar interstitial tissue, the epithelium of the alveoli was relatively large, and as a result hyaline membranes were formed, which consisted of relatively thin fibers. In groups of children who died at 28-32 and 33-37 weeks, an expansion of the area occupied by airborne droplets in the infant's lungs, thinning of interstitial tissue and thickening of hyaline membranes were observed compared to the group of earlier terms.
Keywords:
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:infant, premature birth, lungs, alveoli, hyaline membrane, morphology
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