Nargiza A. Abdurakhmanova
Candidate of Pharmaceutical Sciences, Associate Professor of the Department of Organization of Pharmaceutical Business and Pharmaceutical Technology of the Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan. E-mail: nargiza_24.10.1975@mail.ru
Abstract
By the methods of high performance liquid chromatography and high performance liquid chromatography mass spectrometry in aqueous and aqueous-alcoholic extracts of the choleretic herbal collection "Triflos" phenolcarboxylic acids and flavonoid compounds were determined. By comparing the composition of extractive phenolic compounds of individual plant components with the composition of the extract of a three-component collection, the origin of biologically active components (for substances characteristic of one plant) or the share of each plant in the formation of the total amount of the determined component (for substances originating from all three plants) was revealed.
Purpose of the work: determination of the composition of phenolic compounds and their origin in the extracts of the choleretic collection "Triflos" by HPLC and HPLC-MS.
Keywords:
choleretic herbal collection, polyphenolic compounds, high performance liquid chromatography (HPLC), high performance liquid chromatography mass spectrometry (HPLC-MS), phenol carboxylic acids, flavonoid compounds, chemotaxonomic markers.
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