BIOLOGICALLY ACTIVE SUBSTANCES OF A SEDATIVE DRUG

Zaynab E. Sidametova Doctor of Philosophy in Pharmacy, Associate Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan, e-mail: info@pharmi.uz
Nemat K. Olimov Doctor of Pharmaceutical Sciences, Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan, e-mail: info@pharmi.uz
Dilorom O.Rakhimova Candidate of Medical Sciences, Associate Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan, e-mail: info@pharmi.uz
Barno J.Khasanova Pharmacist, Assistant, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan, e-mail: info@pharmi.uz
Bobir S.Rakhimov Candidate of Medical Sciences, Associate Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan, e-mail: info@pharmi.uz

Abstract

As a result of the research, the amino acid and elemental composition of the liquid extract "Phlegmen" was determined, and it was found that the liquid extract contains 18 amino acids and 39 macro and micro elements. Among the collection of amino acids, glutamic acid prevails, which is used in the treatment of diseases of the central nervous system. It follows from this that the amino acids of the liquid extract under study can participate in the manifestation of the pharmacological activity of the liquid extract. Among the macro and microelements were found: magnesium, a deficiency, which leads to anxiety, fear, confusion, depression. Macronutrients Phosphorus and bromine, which have a pronounced sedative effect and have a beneficial effect on the nervous tissue, restoring performance after emotional and physical stress. The macronutrient lithium, which prevents the development of neuropsychic diseases and has a positive effect on the treatment of schizophrenia. Zinc deficiency is of paramount importance, since it not only leads to underdevelopment of the nervous and reproductive systems, but is also deeply associated with problems of immunodeficiency. T-lymphocytes in conditions of zinc deficiency are inactive. Lithium in the liquid extract contains 0.009%. The data allow us to conclude that the amino acid and elemental composition of the liquid extract is very diverse and can have a complex effect, accordingly.

Keywords:

amino acid, valine, isoleucine, leucine, threonine, methionine, lysine, phenylalanine, tryptophan, histidine, macronutrients.


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