3D PRINTING: A NOVEL APPROACH FOR PREPARATION OF MUCOADHESIVE MICROSPHERE
Neerja Kumari
Noida Institute of Engineering and Technology (Pharmacy Institute), Plot 19, Knowledge Park 2, Greater Noida, Uttar Pradesh-201306, India, neerjakumari0501@gmail.com
Dr. Sushma Verma
Noida Institute of Engineering and Technology (Pharmacy Institute), Plot 19, Knowledge Park 2, Greater Noida, Uttar Pradesh-201306, India.
Abstract
Technology is the primary factor that has altered our lives. Carrier innovation technology gives a fascinating just as a intelligent methodology for the conveyance of medication. It offers conveyance of medication by coupling the medication to a carrier molecule, for Example, microspheres, mucoadhesive microspheres, nanoparticles, liposomes. In drug delivery system the mucoadhesive microspheres mathematical modeling plays an important role in elucidating the important drug release mechanisms, which are classified as diffusion-swelling and erosion-controlled system. Drug delivery system is carried out to develop a gastro retentive dosage form can be improve the drug delivery and performance of drug. The drug to remain in the stomach for a sufficient time interval. At the site of use or ingestion and work with a intimate contact with the fundamental retention surface and subsequently add to improved and better remedial execution of medication and further more mucoadhesive microspheres benefits like effective assimilation and upgraded bioavailability of the medication because of a high surface to volume proportion, a significantly more intimate contact with the bodily fluid layer, controlled and sustained release medication from measurement structure and explicit focusing of medication to the retention site. A novel approach to the Additive manufacturing has evolved in to a mainstream technology that is increasingly competitive to traditional manufacturing processes in terms of cost and process capabilities. A Recent advanced technology an extrusion based three dimensional (3D) printing are Acoustophoretic printing, microvalve based Bio-printing ,inkjet printing, droplet based printing methods are widely common approaches such as inkjet or electro-hydrodynamic printing are well suited only for materials with low viscosity or specific electromagnetic properties respectively. That are now typically harnessed for microspheres printing materials.
Keywords:
Release Mechanism, Mucoadhesive Microspheres, 3Dprinting, Droplet-Based, Bio-ink Printing.Full Text:
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